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Article

Developmental origins of diabetes: the role of epigenetic mechanisms.

Current opinion in endocrinology, diabetes, and obesity - 1 Feb 2007

Simmons Rebecca A

Abstract excerpt

PURPOSE OF REVIEW: Intrauterine growth retardation has been linked to later development of type 2 diabetes. An abnormal intrauterine milieu affects the development of the fetus by permanently modifying gene expression of susceptible cells. Altered gene expression persists after birth suggesting that an epigenetic mechanism may be responsible for changes in transcription. The purpose of this article is to review...

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Source

Identifiers

PMID: 17940413
DOI: 10.1097/MED.0b013e328013da5b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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