Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonreplication of the type 5 17beta-hydroxysteroid dehydrogenase gene association with polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism - 1 Jan 2008

Goodarzi Mark O, Jones Michelle R, Antoine Heath J, Pall Marita, Chen Yii-Der I, Azziz Ricardo

Abstract excerpt

CONTEXT: Increased androgen production is a primary feature of polycystic ovary syndrome (PCOS) and appears to be an inherited trait. The gene for the steroidogenic enzyme type 5 17beta hydroxysteroid dehydrogenase (HSD17B5) was implicated as a candidate for the hyperandrogenemia of PCOS by a previous study that demonstrated an association of a single nucleotide polymorphism (SNP) in the promoter of this gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 17-Hydroxysteroid Dehydrogenases
Share to 3-Hydroxysteroid Dehydrogenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alabama

Share to Cohort Studies

Share to DNA Replication

Share to Logistic Models

Share to Polycystic Ovary Syndrome

Share to Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 17940109
DOI: 10.1210/jc.2007-1712
PMCID: PMC2190745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonreplication of the type 5 17beta-hydroxysteroid dehydrogenase gene association with polycystic ovary syndrome.PMID 17940109Read ↗

Identification of a functional polymorphism of the human type 5 17beta-hydroxysteroid dehydrogenase gene associated with polycystic ovary syndrome.Semantic proximity Read ↗

Association of the 17-hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) with hyperandrogenemia in polycystic ovary syndrome (PCOS).Semantic proximity Read ↗

Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene.Semantic proximity Read ↗

Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage.Semantic proximity Read ↗

Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome.Semantic proximity Read ↗

Variants in the 5alpha-reductase type 1 and type 2 genes are associated with polycystic ovary syndrome and the severity of hirsutism in affected women.Semantic proximity Read ↗

Lack of association between common polymorphisms in the 17beta-hydroxysteroid dehydrogenase type V gene (HSD17B5) and precocious pubarche.Semantic proximity Read ↗

Polymorphisms of the HSD17B6 and HSD17B5 genes in Chinese women with polycystic ovary syndrome.Semantic proximity Read ↗

Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk.Semantic proximity Read ↗

Association of genetic variants in the two isoforms of 5α-reductase, SRD5A1 and SRD5A2, in lean patients with polycystic ovary syndrome.Semantic proximity Read ↗

Genetic variants of the HSD11B1 gene promoter may be protective against polycystic ovary syndrome.Semantic proximity Read ↗

17-Hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) and treatment with oral contraceptive pills in PCOS women without metabolic comorbidities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.