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Article

Association of genetic variants in the two isoforms of 5α-reductase, SRD5A1 and SRD5A2, in lean patients with polycystic ovary syndrome.

European journal of obstetrics, gynecology, and reproductive biology - 1 Aug 2011

Graupp M, Wehr E, Schweighofer N, Pieber T R, Obermayer-Pietsch B

Abstract excerpt

OBJECTIVE: Given its role in converting testosterone to dihydrotestosterone and cortisol to dihydrocortisol, 5α-reductase may be important in the pathophysiology of the polycystic ovary syndrome (PCOS). Increased activity of this enzyme has already been demonstrated in ovaries of affected women, and might be caused by genetic alterations. The aim of this study was to analyze representative genetic variants of...

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Source

Identifiers

PMID: 21530059
DOI: 10.1016/j.ejogrb.2011.03.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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