Article
Magic but treatable? Tumours due to loss of merlin.
Brain : a journal of neurology - 1 Mar 2008
Hanemann C O
Abstract excerpt
Alterations in the NF2 gene coding for merlin cause all tumours that occur in patients suffering from neurofibromatosis type 2, all spontaneous schwannomas and the majority of meningiomas. Thus merlin's tumours are quite frequent and also numerous when inherited as part of meurofibromatosis type 2. Tumours caused by mutations in the NF2 gene are benign and thus do not respond to classical chemotherapy. Surgery...
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