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Article

Prospective Determination of Prevalence of Lynch Syndrome in Young Women With Endometrial Cancer

10 Oct 2007

Abstract excerpt

PURPOSE: Age younger than 50 years at the time of colon cancer diagnosis is often used as a screening criterion for Lynch syndrome (hereditary nonpolyposis colorectal cancer syndrome). The purpose of this study was to determine the prevalence of MLH1, MSH2, and MSH6 mutations in an unselected cohort of women diagnosed with endometrial cancer at age younger than 50 years. METHODS: A prospective, multicenter study...

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Share to Colorectal Cancer Screening and Detection
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Identifiers

PMID: 17925543
DOI: 10.1200/jco.2007.10.8597

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