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Article

Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer.

International journal of colorectal disease - 1 Jan 2008

Yoshida Shiei, Ikehara Nobunao, Aoyama Nobuo, Shirasaka Daisuke, Sakashita Masanori, Semba Shuho, Hasuo Tadateru, Miki Ikuya, Morita Yoshinori, Tamura Takao, Azuma Takeshi, Yokozaki Hiroshi, Kasuga Masato

Abstract excerpt

BACKGROUND AND AIMS: Many investigators have reported flat and depressed lesions as a new type of precursor of colorectal cancer. In our previous study, we determined that mutations in the BRAF gene may contribute to colorectal carcinogenesis by inhibiting apoptosis. However, the relationship among BRAF mutations, morphology and apoptosis in early colorectal cancer has not been clear. Therefore, gene alternation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Gene Expression Regulation, Neoplastic

Share to Genes, ras

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Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 17924122
DOI: 10.1007/s00384-007-0349-0

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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