Article
Generating new candidate genes for neonatal diabetes: functional and genetic studies of insulin secretion in type 2 diabetes.
Endocrine development - 1 Jan 2007
Rutter Guy A
Abstract excerpt
Although the molecular lesions underlying a substantial proportion of all cases of permanent and neonatal diabetes have now been defined, in as many as 30% of cases the defect is unknown. Three complementary approaches may help to define further disease-causing changes: (1) the molecular dissection of the insulin secretory process itself using cellular, physiological and imaging techniques; (2) measurements of...
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