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Article

Development of a novel vascular simulator and injury model to evaluate smooth muscle cell response following balloon angioplasty.

Annals of vascular surgery - 1 Nov 2007

Acampora K Bethany, Langan Eugene M, Miller Richard S, Laberge Martine

Abstract excerpt

Following balloon angioplasty, denudation of endothelial cells exposes vascular smooth muscle cells (SMCs) to normally unseen shear forces from blood flow. In vivo studies investigate the response to angioplasty injury, but limited studies have been performed using in vitro systems. In order to study SMC response in vitro, a concurrent shear and tensile forces simulator has been developed to provide clinically...

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PMID: 17923382
DOI: 10.1016/j.avsg.2007.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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