Article
Increased synthetic phenotype behavior of smooth muscle cells in response to in vitro balloon angioplasty injury model.
Annals of vascular surgery - 1 Jan 2010
Acampora K Bethany, Nagatomi Jiro, Langan Eugene M, LaBerge Martine
Abstract excerpt
Restenosis remains a common problem following balloon angioplasty, and it has been speculated that changes in the mechanical environment due to endovascular interventions are correlated with shifts in smooth muscle cell (SMC) phenotype. In order to study SMC response to forces similar to those exerted during balloon angioplasty, an in vitro concurrent shear and tensile forces simulator has been developed. After...
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