Article
5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol.
Obesity research - 1 Jul 2002
Rosmond Roland, Bouchard Claude, Björntorp Per
Abstract excerpt
OBJECTIVE: There is considerable evidence that cortisol secretion is associated with obesity. The regulation of the 5-hydroxytryptamine receptor 2A (5-HT2A) gene might play an essential role because it is involved in the control of cortisol secretion. Therefore, we examined the potential impact of the 5-HT2A -1438G/A promoter polymorphism on obesity and estimates of insulin, glucose, and lipid metabolism as well...
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