Article
Mutations in DNA repair genes are associated with the Haarlem lineage of Mycobacterium tuberculosis independently of their antibiotic resistance.
Tuberculosis (Edinburgh, Scotland) - 1 Nov 2007
Olano Juanita, López Beatriz, Reyes Alejandro, Lemos María del Pilar, Correa Nidia, Del Portillo Patricia, Barrera Lucia, Robledo Jaime, Ritacco Viviana, Zambrano María Mercedes
Abstract excerpt
The analysis of the DNA repair genes ogt and ung was carried out in 117 Mycobacterium tuberculosis clinical isolates from Argentina and Colombia in order to explore correlation between mutations in these genes and multi-drug resistance. With the exception of two Beijing family isolates, the rest of the strains harbored either two wild-type or two mutant alleles with identical single nucleotide polymorphisms...
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