Further studies on the arrest of cell proliferation in tumor cells at the invading front of colonic adenocarcinoma.

Abstract excerpt

BACKGROUND AND AIM: The author has previously reported that neoplastic glands at the leading invading edge of colorectal carcinomas often display flat tumor cells and cellular gaps called glandular pores. The aim of this study was to audit cell proliferation and p53 mutation in flat tumor cells and in tumor cells at the tip of glandular pores at the leading invading front of colonic carcinomas. METHODS: Sections...

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