Article
Epithelial proliferation and ras p21 oncoprotein expression in rectal mucosa of patients with ulcerative colitis.
Digestive diseases and sciences - 1 May 2001
Ierardi E, Principi M, Francavilla R, Passaro S, Noviello F, Burattini O, Francavilla A
Abstract excerpt
In ulcerative colitis (UC), epithelial proliferation plays a role in crypt repair and neoplastic evolution. Proliferative status is predominantly connoted in active disease, but not defined in remission. Histologically, remission is characterized by normalization of the picture or development of atrophy. Mutation of the ras oncogene is involved in intestinal carcinogenesis. Aim of this work was to assess the...
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