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Article

Classification of advanced colorectal carcinomas by tumor edge morphology: evidence for different pathogenesis and significance of polypoid and nonpolypoid tumors.

Cancer - 1 Nov 2000

George S M, Mäkinen M J, Jernvall P, Mäkelä J, Vihko P, Karttunen T J

Abstract excerpt

BACKGROUND: Increasing evidence suggests that a substantial proportion of colorectal carcinomas develop without a preexisting polypoid adenomatous lesion, but it is difficult to detect the possible origin of advanced carcinomas. The purpose of this study was to test the validity and significance of a new histopathologic classification system based on the histologic analysis of the tumor edge. METHODS: One hundred...

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PMID: 11064346
DOI: 10.1002/1097-0142(20001101)89:9<1901::aid-cncr5>3.3.co;2-r

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