Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modified allele-specific primer-polymerase chain reaction method for analysis of susceptibility of Helicobacter pylori strains to clarithromycin.

Journal of gastroenterology and hepatology - 1 Nov 2007

Furuta Takahisa, Soya Yoshihiro, Sugimoto Mitsushige, Shirai Naohito, Nakamura Akiko, Kodaira Chise, Nishino Masafumi, Okuda Masumi, Okimoto Tadayoshi, Murakami Kazunari, Fujioka Toshio, Hishida Akira

Abstract excerpt

BACKGROUND AND AIM: Most clarithromycin-resistant strains of Helicobacter pylori have a mutation from adenine (A) to guanine (G) at position 2142 or 2143 of the 23S rRNA gene. Our aim in this study was to develop a polymerase chain reaction (PCR)-based assay that could determine these mutations in a single reaction tube. METHODS: We designed the forward primer FP2143G and the reverse primer RP2142G, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clarithromycin
Share to DNA, Ribosomal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Gastritis

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Peptic Ulcer

Share to RNA, Ribosomal, 23S

Source

Identifiers

PMID: 17914955
DOI: 10.1111/j.1440-1746.2007.04919.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modified allele-specific primer-polymerase chain reaction method for analysis of susceptibility of Helicobacter pylori strains to clarithromycin.PMID 17914955Read ↗

Determination of mutations of the 23S rRNA gene of Helicobacter pylori by allele specific primer-polymerase chain reaction method.Semantic proximity Read ↗

Establishment of a nested-ASP-PCR method to determine the clarithromycin resistance of Helicobacter pylori.Semantic proximity Read ↗

PCR using 3'-mismatched primers to detect A2142C mutation in 23S rRNA conferring resistance to clarithromycin in Helicobacter pylori clinical isolates.Semantic proximity Read ↗

Genotypic and Phenotypic Resistance to Clarithromycin in Helicobacter pylori StrainsSemantic proximity Read ↗

Mutations in the 23S rRNA gene of clarithromycin-resistant Helicobacter pylori from Japan.Semantic proximity Read ↗

Helicobacter pylori 23S rRNA gene A2142G, A2143G, T2182C, and C2195T mutations associated with clarithromycin resistance detected in Sudanese patientsSemantic proximity Read ↗

A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori.Semantic proximity Read ↗

Detection of 23SrRNA Mutations Strongly Related to Clarithromycin Resistance in Helicobacter pylori Strains Isolated From Patients in the North of IranSemantic proximity Read ↗

Oligonucleotide microarray: a new rapid method for screening the 23S rRNA gene of Helicobacter pylori for single nucleotide polymorphisms associated with clarithromycin resistance.Semantic proximity Read ↗

Mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance.Semantic proximity Read ↗

Phenotypic and Molecular Antimicrobial Susceptibility of Helicobacter pylori.Semantic proximity Read ↗

Helicobacter pylori 23S rRNA gene A2142G, A2143G, T2182C, and C2195T mutations associated with clarithromycin resistance detected in Sudanese patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.