Article
Phenotypic and Molecular Antimicrobial Susceptibility of Helicobacter pylori.
Antimicrobial agents and chemotherapy - 1 Apr 2017
Chen Derrick, Cunningham Scott A, Cole Nicolynn C, Kohner Peggy C, Mandrekar Jayawant N, Patel Robin
Abstract excerpt
Failure to eradicate Helicobacter pylori infection is often a result of antimicrobial resistance, which for clarithromycin is typically mediated by specific point mutations in the 23S rRNA gene. The purpose of this study was to define current patterns of antimicrobial susceptibility in H. pylori isolates derived primarily from the United States and to survey them for the presence of point mutations in the 23S...
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