Article
Gastrointestinal stromal tumors regularly express synaptic vesicle proteins: evidence of a neuroendocrine phenotype.
Endocrine-related cancer - 1 Sept 2007
Bümming Per, Nilsson Ola, Ahlman Håkan, Welbencer Anna, Andersson Mattias K, Sjölund Katarina, Nilsson Bengt
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are thought to originate from the interstitial cells of Cajal, which share many properties with neurons of the gastrointestinal tract. Recently, we demonstrated expression of the hormone ghrelin in GIST. The aim of the present study was therefore to evaluate a possible neuroendocrine phenotype of GIST. Specimens from 41 GISTs were examined for the expression of 12 different...
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