Article
Complex genetic alterations in gastrointestinal stromal tumors with autonomic nerve differentiation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2002
Debiec-Rychter Maria, Pauwels Patrick, Lasota Jerzy, Franke Sabine, De Vos Rita, De Wever Ivo, Hagemeijer Anne, Sciot Raf
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) with neurogenic differentiation, also referred to as "gastrointestinal autonomic nerve tumors (GANTs)," form an ultrastructurally distinctive subgroup of mesenchymal neoplasms of gastrointestinal tract. Cytogenetic and molecular data of these tumors are limited. In the current study, c-KIT gene sequenc-ing analysis, comparative genomic hybridization (CGH), and interphase...
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