Article
High prevalence of the CD14-159CC genotype in patients infected with severe acute respiratory syndrome-associated coronavirus.
Clinical and vaccine immunology : CVI - 1 Dec 2007
Yuan Fang F, Boehm Ingrid, Chan Paul K S, Marks Katherine, Tang Julian W, Hui David S C, Sung Joseph J Y, Dyer Wayne B, Geczy Andrew F, Sullivan John S
Abstract excerpt
To investigate whether genetic factors of innate immunity might influence susceptibility and/or progression in individuals infected with SARS, we evaluated the CD14 gene polymorphism in 198 Hong Kong blood donors and 152 Hong Kong severe acute respiratory syndrome (SARS) patients who were previously genotyped for FcgammaRIIA polymorphisms. The prevalence of the CD14-159CC polymorphism was significantly higher in...
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