Article
VZV gB endocytosis and Golgi localization are mediated by YXXphi motifs in its cytoplasmic domain.
Virology - 20 Jun 2001
Heineman T C, Hall S L
Abstract excerpt
The cytoplasmic domains of many membrane proteins contain sorting signals that mediate their endocytosis from the plasma membrane. VZV gB contains three consensus internalization motifs within its cytoplasmic domain: YMTL (aa 818-821), YSRV (aa 857-860), and LL (aa 841-842). To determine whether VZV gB is internalized from the plasma membrane, and whether these motifs are required for its endocytosis, we compared...
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