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Article

Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase.

Development (Cambridge, England) - 1 Nov 2007

Bembenek Joshua N, Richie Christopher T, Squirrell Jayne M, Campbell Jay M, Eliceiri Kevin W, Poteryaev Dmitry, Spang Anne, Golden Andy, White John G

Abstract excerpt

In many organisms, cortical granules undergo exocytosis following fertilization, releasing cargo proteins that modify the extracellular covering of the zygote. We identified cortical granules in Caenorhabditis elegans and have found that degranulation occurs in a wave that initiates in the vicinity of the meiotic spindle during anaphase I. Previous studies identified genes that confer an embryonic osmotic...

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Identifiers

PMID: 17913784
DOI: 10.1242/dev.011361
PMCID: PMC5507579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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