Article
Amplification of <i>PVT1</i> Contributes to the Pathophysiology of Ovarian and Breast Cancer
1 Oct 2007
Abstract excerpt
PURPOSE: This study was designed to elucidate the role of amplification at 8q24 in the pathophysiology of ovarian and breast cancer because increased copy number at this locus is one of the most frequent genomic abnormalities in these cancers. EXPERIMENTAL DESIGN: To accomplish this, we assessed the association of amplification at 8q24 with outcome in ovarian cancers using fluorescence in situ hybridization to...
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