Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis.

PloS one - 1 Jan 2016

Iden Marissa, Fye Samantha, Li Keguo, Chowdhury Tamjid, Ramchandran Ramani, Rader Janet S

Abstract excerpt

The plasmacytoma variant translocation 1 gene (PVT1) is an lncRNA that has been designated as an oncogene due to its contribution to the phenotype of multiple cancers. Although the mechanism by which PVT1 influences disease processes has been studied in multiple cancer types, its role in cervical tumorigenesis remains unknown. Thus, the present study was designed to investigate the role of PVT1 in cervical cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cisplatin
Share to Gene Silencing
Share to Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphoproteins

Share to Proto-Oncogene Proteins c-myc

Share to RNA-Binding Proteins

Share to RNA, Long Noncoding

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 27232880
DOI: 10.1371/journal.pone.0156274
PMCID: PMC4883781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis.PMID 27232880Read ↗

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinomaSemantic proximity Read ↗

PVT1 Long Non-coding RNA in Gastrointestinal CancerSemantic proximity Read ↗

PVT1 Assumes Signifying Capacity in Cervical Cancer Diagnosis.Semantic proximity Read ↗

Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer CellsSemantic proximity Read ↗

Long Noncoding RNA PVT1 Promotes Breast Cancer Proliferation and Metastasis by Binding mIR-128-3p and UPF1Semantic proximity Read ↗

lncRNA PVT1 identified as an independent biomarker for prognosis surveillance of solid tumors based on transcriptome data and meta-analysisSemantic proximity Read ↗

Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancerSemantic proximity Read ↗

Long noncoding RNA plasmacytoma variant translocation 1 promotes progression of colorectal cancer by sponging microRNA‐152‐3p and regulating E2F3/MAPK8 signalingSemantic proximity Read ↗

High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanomaSemantic proximity Read ↗

LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA.Semantic proximity Read ↗

LncRNA PVT1 is increased in renal cell carcinoma and affects viability and migration in vitroSemantic proximity Read ↗

Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.