Article
Capturing heterogeneity in gene expression studies by surrogate variable analysis.
PLoS genetics - 1 Sept 2007
Leek Jeffrey T, Storey John D
Abstract excerpt
It has unambiguously been shown that genetic, environmental, demographic, and technical factors may have substantial effects on gene expression levels. In addition to the measured variable(s) of interest, there will tend to be sources of signal due to factors that are unknown, unmeasured, or too...
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