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Article

Renal insufficiency in non-diabetic subjects: relationship of MTHFR C677t gene polymorphism and left ventricular hypertrophy.

Renal failure - 1 Jan 2013

Trovato Guglielmo M, Catalano Daniela, Ragusa Angela, Martines G Fabio, Tonzuso Antonia, Pirri Clara, Buccheri Maria Antonietta, Di Nora Concetta, Trovato Francesca M

Abstract excerpt

BACKGROUND: Association of methylenetetrahydrofolate reductase (MTHFR) 677C>T gene polymorphism with hyperhomocysteinemia, renal failure, and cardiovascular events is controversial. We investigated the relationship of MTHFR 677C>T polymorphisms with left ventricular hypertrophy (LVH) and renal insufficiency. METHODS: Glomerular filtration rate (GFR) and left myocardial ventricular mass/m2 were assessed in 138...

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Identifiers

PMID: 23534584
DOI: 10.3109/0886022X.2013.779895

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Renal insufficiency in non-diabetic subjects: relationship of MTHFR C677t gene polymorphism and left ventricular hypertrophy.PMID 23534584Read ↗

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