Article
Gene expression in endoprosthesis loosening: chitinase activity for early diagnosis?
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Mar 2008
Morawietz L, Weimann A, Schroeder J H, Kuban R J, Ungethuem U, Kaps C, Slevogt H, Gehrke T, Krukemeyer M G, Krenn V
Abstract excerpt
The aim of the study was to identify markers for the early diagnosis of endoprosthesis loosening, for the differentiation between wear particle-induced and septic loosening and to gather new insights into the pathogenesis of endoprosthesis loosening. Gene expression profiles were generated from five periprosthetic membranes of wear particle-induced and five of infectious (septic) type using Affymetrix HG U133A...
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