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Article

Mitochondrial changes in leukocytes of patients with optic neuritis.

Molecular vision - 29 Aug 2007

Bosley Thomas M, Constantinescu Cris S, Tench Christopher R, Abu-Amero Khaled K

Abstract excerpt

PURPOSE: Optic neuritis (ON) is a demyelinating disorder affecting optic nerves. It has certain similarities to Leber hereditary optic neuropathy (LHON) and other spontaneous optic neuropathies known to be associated with mitochondriopathies. We evaluated patients with optic neuritis for evidence of systemic mitochondrial abnormalities. METHODS: Patients were selected who had ON affecting one or both eyes. We...

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Source

Identifiers

PMID: 17893651

Genes

OPA1
OPA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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