Article
HDAC10 promoter polymorphism associated with development of HCC among chronic HBV patients.
Biochemical and biophysical research communications - 23 Nov 2007
Park Byung Lae, Kim Yoon Jun, Cheong Hyun Sub, Lee Soo Ok, Han Chang Soo, Yoon Jung-Hwan, Park Ju Hyun, Chang Hun Soo, Park Choon-Sik, Lee Hyo-Suk, Shin Hyoung Doo
Abstract excerpt
Histone deacetylases (HDACs) are key enzymes responsible for the removal of acetyl groups from acetylated histone and non-histone proteins, and play important roles in various biological processes including transcription regulation and DNA repair. In this study, we identified 22 sequence variants by direct DNA sequencing in 24 individuals and five common variant were selected for genotyping in larger-scale...
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