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Article

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans.

Genetics - 1 Sept 2007

Aladzsity István, Tóth Márton L, Sigmond Tímea, Szabó Emese, Bicsák Bertalan, Barna János, Regos Agnes, Orosz László, Kovács Attila L, Vellai Tibor

Abstract excerpt

Here we show that in the nematode Caenorhabditis elegans mutational inactivation of two autophagy genes unc-51/atg1 and bec-1/atg6/beclin1 results in small body size without affecting cell number. Furthermore, loss-of-function mutations in unc-51 and bec-1 suppress the giant phenotype of mutant a...

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Identifiers

PMID: 17890369
DOI: 10.1534/genetics.107.075762
PMCID: PMC2013693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17890369-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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