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Article

Structural and functional characterization of human telomerase RNA processing and cajal body localization signals.

Molecular cell - 21 Sept 2007

Theimer Carla A, Jády Beáta E, Chim Nicholas, Richard Patricia, Breece Katherine E, Kiss Tamás, Feigon Juli

Abstract excerpt

The RNA component of human telomerase (hTR) includes H/ACA and CR7 domains required for 3' end processing, localization, and accumulation. The terminal loop of the CR7 domain contains the CAB box (ugAG) required for targeting of scaRNAs to Cajal bodies (CB) and an uncharacterized sequence required for accumulation and processing. To dissect out the contributions of the CR7 stem loop to hTR processing and...

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Identifiers

PMID: 17889661
DOI: 10.1016/j.molcel.2007.07.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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