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Article

IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2008

Isomura Minoru, Oya Natsuo, Tachiiri Seiji, Kaneyasu Yuko, Nishimura Yasumasa, Akimoto Tetsuo, Hareyama Masato, Sugita Tadasi, Mitsuhashi Norio, Yamashita Takashi, Aoki Masahiko, Sai Heitetsu, Hirokawa Yutaka, Sakata Koh-Ichi, Karasawa Kumiko, Tomida Akihiro, Tsuruo Takashi, Miki Yoshio, Noda Tetsuo, Hiraoka Masahiro

Abstract excerpt

PURPOSE: Severe acute radiation dermatitis is observed in approximately 5% to 10% of patients who receive whole-breast radiotherapy. Several factors, including treatment-related and patient-oriented factors, are involved in susceptibility to severe dermatitis. Genetic factors are also thought to be related to a patient's susceptibility to severe dermatitis. To elucidate genetic polymorphisms associated with a...

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Identifiers

PMID: 18927311
DOI: 10.1158/1078-0432.CCR-07-4389

Genes

ABCA1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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