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Article

A quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species.

Proceedings of the National Academy of Sciences of the United States of America - 2 Oct 2007

Freimer Nelson B, Service Susan K, Ophoff Roel A, Jasinska Anna J, McKee Kevin, Villeneuve Amelie, Belisle Alexandre, Bailey Julia N, Breidenthal Sherry E, Jorgensen Matthew J, Mann J John, Cantor Rita M, Dewar Ken, Fairbanks Lynn A

Abstract excerpt

Non-human primates (NHP) provide crucial research models. Their strong similarities to humans make them particularly valuable for understanding complex behavioral traits and brain structure and function. We report here the genetic mapping of an NHP nervous system biologic trait, the cerebrospinal fluid (CSF) concentration of the dopamine metabolite homovanillic acid (HVA), in an extended inbred vervet monkey...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17884980
DOI: 10.1073/pnas.0707640104
PMCID: PMC1987389

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Source receipt: pubmed, retrieved 7 Sept 2026.

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