Article
Genetics of monoamine metabolites in baboons: overlapping sets of genes influence levels of 5-hydroxyindolacetic acid, 3-hydroxy-4-methoxyphenylglycol, and homovanillic acid.
Biological psychiatry - 1 Apr 2004
Rogers Jeffrey, Martin Lisa J, Comuzzie Anthony G, Mann J John, Manuck Stephen B, Leland Michelle, Kaplan Jay R
Abstract excerpt
BACKGROUND: Monoamine neurotransmitters (serotonin, dopamine, and norepinephrine) are associated with several psychiatric disorders. Limited evidence suggests that monoamine levels are heritable, but no information concerning genetic relationships among monoamines is available. Further genetic analysis can help explain phenotypic correlations among monoamine levels and might eventually help identify genes...
Topics
- Analysis of Variance
- Animals
- Animals, Newborn
- Female
- Gene Expression
- Genetic Variation
- Genotype
- Homovanillic Acid
- Hydroxyindoleacetic Acid
- Likelihood Functions