Article
Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction.
Circulation - 9 Oct 2007
Segers Vincent F M, Tokunou Tomotake, Higgins Luke J, MacGillivray Catherine, Gannon Joseph, Lee Richard T
Abstract excerpt
BACKGROUND: Local delivery of chemotactic factors represents a novel approach to tissue regeneration. However, successful chemokine protein delivery is challenged by barriers including the rapid diffusion of chemokines and cleavage of chemokines by proteases that are activated in injured tissues....
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