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Article

Phenotype of the taurine transporter knockout mouse.

Methods in enzymology - 1 Jan 2007

Warskulat Ulrich, Heller-Stilb Birgit, Oermann Evelyn, Zilles Karl, Haas Helmut, Lang Florian, Häussinger Dieter

Abstract excerpt

This chapter reports present knowledge on the properties of mice with disrupted gene coding for the taurine transporter (taut-/- mice). Study of those mice unraveled some of the roles of taurine and its membrane transport for the development and maintenance of normal organ functions and morphology. When compared with wild-type controls, taut-/- mice have decreased taurine levels in skeletal and heart muscle by...

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PMID: 17875433
DOI: 10.1016/S0076-6879(07)28025-5

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