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Article

Tissue depletion of taurine accelerates skeletal muscle senescence and leads to early death in mice.

PloS one - 1 Jan 2014

Ito Takashi, Yoshikawa Natsumi, Inui Takaaki, Miyazaki Natsuko, Schaffer Stephen W, Azuma Junichi

Abstract excerpt

Taurine (2-aminoethanesulfonic acid) is found in milimolar concentrations in mammalian tissues. One of its main functions is osmoregulation; however, it also exhibits cytoprotective activity by diminishing injury caused by stress and disease. Taurine depletion is associated with several defects, many of which are found in the aging animal, suggesting that taurine might exert anti-aging actions. Therefore, in the...

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Identifiers

PMID: 25229346
DOI: 10.1371/journal.pone.0107409
PMCID: PMC4167997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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