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Article

A non-canonical Grb2-PLC-gamma1-Sos cascade triggered by lipovitellin 1, an apolipoprotein B homologue.

Cellular signalling - 1 Dec 2007

Browaeys-Poly Edith, Broutin Isabelle, Antoine Anne-Frédérique, Marin Matthieu, Lescuyer Arlette, Vilain Jean Pierre, Ducruix Arnaud, Cailliau Katia

Abstract excerpt

The injection of the Grb2 adapter in Xenopus oocytes promotes G2/M transition without stimulation from a receptor only the first day after the oocytes removal from the ovaries. This cell cycle reinitiation is Ras-dependent and requires the SH2 and SH3 domains of Grb2. The SH2 domain of Grb2 binds...

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Identifiers

PMID: 17869481
DOI: 10.1016/j.cellsig.2007.08.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17869481-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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