Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.

Molecular biology of the cell - 1 Nov 2007

Mejlvang Jakob, Kriajevska Marina, Vandewalle Cindy, Chernova Tatyana, Sayan A Emre, Berx Geert, Mellon J Kilian, Tulchinsky Eugene

Abstract excerpt

Zinc finger transcription factors of the Snail/Slug and ZEB-1/SIP1 families control epithelial-mesenchymal transitions in development in cancer. Here, we studied SIP1-regulated mesenchymal conversion of epidermoid A431 cells. We found that concomitant with inducing invasive phenotype, SIP1 inhibi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Cycle
Share to Cyclin D1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Epithelial Cells

Share to Mesoderm

Share to Nerve Tissue Proteins

Share to RNA-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17855508
DOI: 10.1091/mbc.e07-05-0406
PMCID: PMC2043563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17855508-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition.PMID 17855508Read ↗

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions.Semantic proximity Read ↗

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer.Semantic proximity Read ↗

Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling.Semantic proximity Read ↗

Cyclin-Dependent Kinase 4–Mediated Phosphorylation Inhibits Smad3 Activity in Cyclin D–Overexpressing Breast Cancer CellsSemantic proximity Read ↗

Mechanisms of transforming growth factor β induced cell cycle arrest in palate development.Semantic proximity Read ↗

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.Semantic proximity Read ↗

Differential Regulation of Epithelial and Mesenchymal Markers by δEF1 Proteins in Epithelial–Mesenchymal Transition Induced by TGF-βSemantic proximity Read ↗

Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.Semantic proximity Read ↗

Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells.Semantic proximity Read ↗

The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain.Semantic proximity Read ↗

Cyclin D1 Functions in Cell MigrationSemantic proximity Read ↗

Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.