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Article

Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells.

Oncogene - 28 Feb 2002

Grinstein Edgar, Jundt Franziska, Weinert Inge, Wernet Peter, Royer Hans-Dieter

Abstract excerpt

Sp1 binding sites have been identified in enhancer/promoter regions of several growth and cell cycle regulated genes, and it has been shown that Sp1 is increasingly phosphorylated in G1 phase of the cell cycle. Interactions of Sp1 with proteins involved in control of cell cycle and tumor formation have been reported. Here we show that expression of Sp1 protein predominates in the G1 phase of the cell cycle in...

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PMID: 11896576
DOI: 10.1038/sj.onc.1205211

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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