Article
[Mutations altering the specificity of the sensor RNA encoded by the Bacillus subtilis pbuE gene].
Genetika - 1 Jun 2007
Lobanov K V, Korol'kova N V, Eremina S Iu, Errais Lopes L, Proshkin S A, Mironov A S
Abstract excerpt
Site-directed mutagenesis was used to study the leader region of the Bacillus subtilis pbuE gene, which codes for adenine-specific sensor RNA. Two nucleotide substitutions, 70U --> C and A100 --> G, in the conserved region (A box) of the leader changed the specificity of the sensor RNA in vivo: guanine acted as a positive transcription effector in place of adenine.
Topics
- Bacillus subtilis
- Base Sequence
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Bacterial