Article
Rab and Arf proteins in genetic diseases.
Traffic (Copenhagen, Denmark) - 1 Aug 2013
Seixas Elsa, Barros Mafalda, Seabra Miguel C, Barral Duarte C
Abstract excerpt
Rab and ADP-ribosylation factor (Arf) family proteins are master regulators of membrane trafficking and are involved in all steps of vesicular transport. These families of small guanine-nucleotide-binding (G) proteins are well suited to regulate membrane trafficking processes since their nucleotide state determines their conformation and the capacity to bind to a multitude of effectors, which mediate their...
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