Article
Metabolome Based Reaction Graphs of M. tuberculosis and M. leprae: A Comparative Network Analysis
11 Sept 2007
Abstract excerpt
BACKGROUND: Several types of networks, such as transcriptional, metabolic or protein-protein interaction networks of various organisms have been constructed, that have provided a variety of insights into metabolism and regulation. Here, we seek to exploit the reaction-based networks of three organisms for comparative genomics. We use concepts from spectral graph theory to systematically determine how differences...