Article
Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2007
Kano Takashi, Mori Takahide, Furudono Masako, Ishikawa Hironobu, Watanabe Hirohiko, Kikkawa Eri, Warita Takayuki, Onizuka Makoto, Takahashi Megumi, Maeda Yutaka, Naruse Taeko, Inoko Hidetoshi, Kimura Akinori
Abstract excerpt
PROBLEM: Recurrent spontaneous abortion (RSA) is defined by at least three consecutive abortions in otherwise healthy couples. Paternal lymphocyte alloimmunization therapy (PLAT) is an effective therapy for RSA in some cases, but there are no predictive markers about the effectiveness of PLAT. METHOD OF STUDY: Forty-two consecutive cases with primary RSA treated by PLAT and 23 controls were the subjects....
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