Article
Diversity of HLA-DR2 in North Indians: the changed scenario after the discovery of DRB1*1506.
Tissue antigens - 1 Aug 1998
Rani R, Mukherjee R, Stastny P
Abstract excerpt
DRB1*1506, a new allele of DR2, differs from DRB1*1501 only at codon 50 in the second exon, where the nucleotide sequence has changed from GTG to GCG resulting in an amino acid substitution from valine to alanine in DRB1*1506. Since codon 50 was considered non-polymorphic until the discovery of t...
Topics
- Alleles
- Genetic Variation
- HLA-DR Antigens
- HLA-DR2 Antigen
- HLA-DRB1 Chains
- Haplotypes
- Humans
- India
- Mutation
- Polymorphism, Genetic