Article
Polymerase chain reaction--based sequence-specific oligonucleotide hybridization analysis of HLA class II antigens in pulmonary tuberculosis: relevance to chemotherapy and disease severity.
The Journal of infectious diseases - 1 Mar 1996
Rajalingam R, Mehra N K, Jain R C, Myneedu V P, Pande J N
Abstract excerpt
HLA antigens were studied by serology and polymerase chain reaction-based sequence-specific oligonucleotide hybridization techniques in 153 patients with pulmonary tuberculosis (PTB) and 289 healthy controls. HLA-DR2 was present more frequently in PTB patients than in controls (51% vs. 36.3%; cor...
Topics
- Adult
- Alleles
- Antitubercular Agents
- Base Sequence
- DNA Primers
- Female
- HLA-DR Antigens
- HLA-DR2 Antigen
- Humans
- Male
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Tuberculosis, Pulmonary