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Article

Copy number variation of the activating FCGR2C gene predisposes to idiopathic thrombocytopenic purpura.

Blood - 1 Feb 2008

Breunis Willemijn B, van Mirre Edwin, Bruin Marrie, Geissler Judy, de Boer Martin, Peters Marjolein, Roos Dirk, de Haas Masja, Koene Harry R, Kuijpers Taco W

Abstract excerpt

Gene copy number variation (CNV) and single nucleotide polymorphisms (SNPs) count as important sources for interindividual differences, including differential responsiveness to infection or predisposition to autoimmune disease as a result of unbalanced immunity. By developing an FCGR-specific multiplex ligation-dependent probe amplification assay, we were able to study a notoriously complex and highly homologous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17827395
DOI: 10.1182/blood-2007-03-079913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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