Article
Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jan 2008
Whittaker Paul, Clarke Jane J, San Richard H C, Betz Joseph M, Seifried Harold E, de Jager Lowri S, Dunkel Virginia C
Abstract excerpt
Kava (Piper methysticum) is a member of the pepper family and has been cultivated by South Pacific islanders for centuries and used as a social and ceremonial drink. Traditionally, kava extracts are prepared by grinding or chewing the rhizome and mixing with water and coconut milk. The active constituents of kava are a group of approximately 18 compounds collectively referred to as kavalactones or kava pyrones....
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