Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism in signal transduction is a major route through which osteoarthritis susceptibility is acting.

Current opinion in rheumatology - 1 Sept 2005

Loughlin John

Abstract excerpt

PURPOSE OF REVIEW: In the last year there has been considerable success in the identification of genes harbouring susceptibility for primary osteoarthritis. This report brings the reader up-to-date by focusing on three of the more compelling finds. RECENT FINDINGS: A UK group reported an association of the FRZB gene with hip osteoarthritis in females. FRZB codes for secreted frizzled-related protein 3, an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calmodulin
Share to Carrier Proteins
Share to Extracellular Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycoproteins

Share to Intracellular Signaling Peptides and Proteins

Share to Osteoarthritis

Share to Polymorphism, Genetic

Share to Signal Transduction

Source

Identifiers

PMID: 16093844
DOI: 10.1097/01.bor.0000176687.85198.49

Genes

ASPN
CALM1
FRZB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism in signal transduction is a major route through which osteoarthritis susceptibility is acting.PMID 16093844Read ↗

New gene associations in osteoarthritis: what do they provide, and where are we going?Semantic proximity Read ↗

The genetic epidemiology of human primary osteoarthritis: current statusSemantic proximity Read ↗

Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.Semantic proximity Read ↗

Functional effects of susceptibility genes in osteoarthritis.Semantic proximity Read ↗

Expression, regulation and function of asporin, a susceptibility gene in common bone and joint diseases.Semantic proximity Read ↗

The clinical relevance of genetic susceptibility to osteoarthritis.Semantic proximity Read ↗

Etiology of osteoarthritis: genetics and synovial joint development.Semantic proximity Read ↗

Insights from human genetic studies into the pathways involved in osteoarthritis.Semantic proximity Read ↗

[Asporin, a susceptibility gene for osteoarthritis].Semantic proximity Read ↗

Secreted frizzled-related protein 3 was genetically and functionally associated with developmental dysplasia of the hip.Semantic proximity Read ↗

Genetic factors in OA pathogenesis.Semantic proximity Read ↗

Expression and Regulation of the Osteoarthritis-associated Protein AsporinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.