Article
DNA enzyme immunoassay: a rapid and convenient colorimetric method for diagnosis of cystic fibrosis.
Molecular and cellular probes - 1 Dec 1991
Mazza C, Mantero G, Primi D
Abstract excerpt
Genetic analysis of inherited diseases has been greatly facilitated by new approaches, involving genomic DNA amplification by the polymerase chain reaction (PCR), followed by hybridization with wild type-specific or mutation-specific oligonucleotide (MSO) probes. The main advantage of these methods is that they allow easy detection of point mutations starting from minimal amounts of biological materials. These...
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