Article
Methylene blue as an electrochemical indicator for DF508 cystic fibrosis mutation detection.
Analytical and bioanalytical chemistry - 1 Feb 2010
Nasef Hany, Beni Valerio, O'Sullivan Ciara K
Abstract excerpt
Cystic fibrosis is one of the most common life-shortening, childhood-onset inherited diseases. Among the 1,000 known cystic fibrosis-related mutations, DF508 is the most common, with a frequency varying between 50% and 70% according to geographical areas and population typology. In this work, we report the use of methylene blue as an electrochemical reporting agent in the discrimination of synthetic PCR analogue...
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